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TEST TO DISTINGUISH CLASSES OF ALCOHOLS
Monday, March 21, 2016



Lucas test

Lucas test in alcohols is a test to differentiate between primary, secondary, and tertiary alcohols. It is based on the difference in reactivity of the three classes of alcohols with hydrogen halides via an SN1 reaction
ROH + HCl → RCl + H2O
The differing reactivity reflects the differing ease of formation of the corresponding carbocations. Tertiary carbocations are far more stable than secondary carbocations, and primary carbocations are the least stable.
An equimolar mixture of ZnCl2 and HCl is the reagent. The alcohol is protonated by this mixture, and H2O group attached to carbon is replaced by the nucleophile Cl−, which is present in excess. Tertiary alcohols react immediately with Lucas reagent as evidenced by turbidity owing to the low solubility of the organic chloride in the aqueous mixture. Secondary alcohols react within five or so minutes (depending on their solubility). Primary alcohols do not react appreciably with Lucas reagent at room temperature. Hence, the time taken for turbidity to appear is a measure of the reactivity of the class of alcohol, and this time difference is used to differentiate among the three classes of alcohols:
  • no visible reaction at room temperature and forming an oily layer only on heating: primary, such as 1-pentanol
  • solution forms oily layer in 3–5 minutes: secondary, such as 2-pentanol
  • solution forms oily layer immediately: tertiary, such as 2-methyl-2-butanol
posted by bamgold @ 6:31 PM  
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